Revenue Forecast Calculator

Free Online Tool – Drug Revenue Forecast Model That Accommodates Multiple Indications and Basic/ Advanced Inputs
Building your own drug revenue forecast model from scratch is time consuming. Instead, you can test your product and market assumptions using our flexible revenue forecast tool below. First, decide on geography (U.S., EU5, or Japan). Then, start adding indications for your investigational therapeutic. The tool has built-in prevalence and incidence data for over 170 diseases.

For tips and clarifications, consult with information boxes next to inputs or send us a message. For real-world examples, check our multiple-choice questions below.
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Confused or stuck? Please send any questions, comments, and requests to bioheights@pm.me.

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Disclaimer: This model/ calculator is the property of BioHeights LLC. The model is designed only for educational purposes. This is not a financial advice. BioHeights LLC and its members are not responsible for anybody’s actions, losses, or damages resulting from using this model.

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Solve a Problem: ALL Pricing

You are developing a drug for acute lymphoblastic leukemia (ALL) and can treat a patient with just a single one-time infusion. You can treat all only 10% of patients. You have no competition. Assume: other parameters are default, except price; only U.S. market.

1. What is the price (per patient) you should charge for the drug if you must generate at least $150M in revenue by Year 5 after launch given incurred R&D and Commercial expenses and milestones/royalties commitments?
  X   Less than $5,000
  X   $5,000
  X   $130,000
  X   $240,000
  X   $400,000
  V   More than $400,000


Solve a Problem: ALL Geography

Same inputs as for Pricing Problem above. Now, you are launching the same drug in EU5. U.S. Launch is expected in 2026. EU5 Launch is expected in 2 years after U.S. Price is 70% of that in the U.S. Price does now grow in EU5. No EU5 discounts/rebates.

1. What is the ratio of U.S. to EU5 revenue for the drug in year 2032?
  X   U.S. : EU5 = 1 : 2
  X   U.S. : EU5 = 1 : 1
  X   U.S. : EU5 = 1.5 : 1
  V   U.S. : EU5 = 2 : 1
  X   I do not know. This requires differential equations and string theory mastery.

2. Should you file for Orphan Drug Designation in EU?
  X   No, I have a patent
  V   Yes
  X   How much does it cost to file ODD?
  X   What is ODD?


Solve a Problem: SMA1 Pricing

You are developing a drug for Spinal Muscular Atrophy Type 1 (SMA1). You can treat all SMA1 patients with just a single one-time infusion. You have no competition. Assume: other parameters are default, except price; only U.S. market.

1. What is the price (per patient) you should charge for the drug if you must generate at least $500M in revenue by Year 5 after launch given incurred R&D and Commercial expenses and milestones/royalties commitments?
  X   less than $10,000
  X   $10,000
  X   $100,000
  X   $500,000
  X   $1,000,000
  V   more than $1,000,000

2. Does the price threshold depend on whether the drug can treat prevalent patients or only incident patients (new cases)?
  X   Same minimum price
  X   If prevalent patients, then price is higher
  V   If only new cases, then price is higher


Solve a Problem: SMA1 Geography

Same inputs as for the SMA1 Pricing problem above. Now, you are launching the same drug in EU5. U.S. Launch in 2026. EU5 Launch is expected in 2 years after U.S. Price is 70% of that in the U.S. Price does now grow in EU5.

1. What is the ratio of U.S. to EU5 revenue for the drug in year 2032?
  X   U.S. : EU5 = 1 : 2
  X   U.S. : EU5 = 1.5 : 1
  X   U.S. : EU5 = 2 : 1
  V   U.S. : EU5 = 2.5 : 1
  X   I do not know. This requires differential equations and string theory mastery.